Two hundred hypertensive patients are randomized to eight a diet program or and

Question

Two hundred hypertensive patients are randomized to eight a diet program or and exercise program(102 patients to diet program, 98 patients to exercise program). Blood pressure is measured on each patient both before the programs start and 3months after the start of each program. The correct statistical procedure to determine whether or not the mean blood pressure change(after-before)was statistically significantly different for the two program is: A. Paired t-test B. 2 sample unpaired t-test C. Fisher's exact test D. Pearson correlation E. None of the above.

Explanation / Answer

Paired t test is used to compare two population means where there are two samples in which observations in one sample can be paired with observations in the other sample. Paired t-test compares study subjects at two different times (paired observations of the same subject) whereas unpaired t-test compares two different subjects.

The Fisher's exact test is useful for categorical data that result from classifying objects in two different ways therefore it is used to examine the significance of the association between the two kinds of classification where as Pearson’s correlation coefficient is the test statistics that measures the statistical relationship, or association, between two continuous variables.

Therefore for the above test the correct statistical procedure is Paired t-test.

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