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Benzodiazepines produce their effects by Enhancing the inhibitory actions of GAB

ID: 179227 • Letter: B

Question

Benzodiazepines produce their effects by Enhancing the inhibitory actions of GABA Acting as an inverse agonist to increase excitatory neurotransmission Decreasing inhibitory tone Inhibiting the release of dopamine That benzodiazepines can function as anti-anxiety drugs is shown by the observation that they Lead to addiction increase punished but not rewarded behaviour Produce state dependent learning Decrease exploration on the plus maze The behavioral effects of benzodiazepines include increased aggression increased frequency of panic attacks anterograde memory loss decrease in the performance of rewarded behaviour Withdrawal from benzodiazepines can be complicated by Therapeutic failure Its high abuse potential Decreased reinforcement Symptoms re-emergence Antidepressants may be used to treat anxiety disorders anxiety because The side effects of the SSRIs are more tolerable than those of the anxiolytic drugs The antidepressant desipramine is particularl

Explanation / Answer

Answer:

1). A). Enhancing the inhibitory actions of GABA

Benzodiazepines produce their therapeutic effects by enhancing the action of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. GABA is the main inhibitory neurotransmitter in the brain, acting through widespread short-and long- projection neurons

2). A. Lead to addiction

Besides the therapeutic effects, all benzodiazepines have an addictive potential and strong withdrawal effect upon cessation of treatment.

3). C. Anterograde memory loss

The side effects of benzodiazepines are drowsiness, sedation, confusion, amnesia (loss of memory) and impaired coordination.

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