37. How RITS identify the target gene to modify its DNA? A. It uses the guide si

Question

37. How RITS identify the target gene to modify its DNA?
A. It uses the guide siRNA that hybridizes with the target DNA
B. It uses the guide siRNA that hybridizes with the mRNA being transcribed from the target gene
C. It uses co-regulators such as HATS and HDACs that recognizes the histones of the nucleosomes
D. Two of these options may be correct
E. All of these options may be correct.

38. As much 60% of some mammalian and plant genomes is made of transposons yet transposition is rare. The most important reason for the rarity of transposition is __________.
A. piRNA
B. transposons lack promoters
C. transposons are in the heterochromatin
D. eukaryotic transposons are mostly DNA transposons

Explanation / Answer

37. Answer Option B.

The direct base pairing interactions between siRNAs and target mRNAs is needed for recognition of a target mRNA by RISC. It leads to mRNA degrdataion or translational inactivation. It leads to inhibition of protein expression and the process is defined as posttranscriptional gene silencing.

38. Answer option A.

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