These are questions from molecular genetics quiz Please help me completing them

Question

These are questions from molecular genetics quiz Please help me completing them in less than an hour :/ ok x f Facebook x W Comparative ge x Dr. Hussam N. x G Ro es/32206/quizzes/67919/take ll have one hour to complete the quiz so please plan accordingly. Question 1 Match the DNA lesion with the typical cause/example: incorrect base l Choose Choose polymerase errors deletion/insertion Radiation intercalating agent UV light single/double stranded break Choose Thymidine dimers I Choose Question 2 What is the significance of DNA methylation in mismatch repair?

Explanation / Answer

1. a) The DNA sequence can be changed as a result of copying errors introduced by DNA polymerases during replication and by environmental agents such as mutagenic chemicals .

b) Insertion is a mutation in which extra base pairs are inserted into a new place in the DNA. Insertion occurs due to DNA polymerase slippage. Deletions are mutations in which a certain section of DNA is lost or deleted.

c) DNA double stranded break is the principle cytotoxic lesion for ionizing radiations but can also be caused by mechanical stress on the chromosomes.

d) The UV light induces the formation of covalent linkages by reactions localized on C=C double bonds.

Related Questions

Navigate

• Browse (All)
• Browse T
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.