Which of the following statements concerning the clonal expansion theory for tum
ID: 178025 • Letter: W
Question
Which of the following statements concerning the clonal expansion theory for tumor development is TRUE?
A
Clonal expansion is a linear progression
Clonal expansion can give rise to different cell populations, resulting in tumors that are comprised of multiple cellular patches
Clonal expansion takes only 1-2 cellular generations to produce a tumor
Clonal expansion is initiated by at least 2 mutations in the first generation of cells
Clonal expansion is a linear progression
B.Clonal expansion can give rise to different cell populations, resulting in tumors that are comprised of multiple cellular patches
C.Clonal expansion takes only 1-2 cellular generations to produce a tumor
D.Clonal expansion is initiated by at least 2 mutations in the first generation of cells
Explanation / Answer
The following statements concerning the clonal expansion theory for tumor development is TRUE;
A: Clonal expansion is a linear progression as just like a population of animals undergoes evolution, an unchecked population of cells also can undergo evolution. This undesirable process is called somatic evolution, and is how cancer arises and becomes more malignant, (Nowell )
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