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Human A&P Which of the following is TRUE of the complement system? Activated com

ID: 177258 • Letter: H

Question

Human A&P Which of the following is TRUE of the complement system? Activated complement proteins can cause cytolysis of microbial invaders. Activated complement proteins may act as costimulators to B. The major function of plasma cells is to secrete complement system proteins. The complement system attacks and and kills microbes bearing the specific antigen that elicited (caused) their production. a and b Imagine tracing the activity of one individual cell from each of the five kinds listed below. Which individual cell can attack and kill the broadest array of microbial pathogens? natural killer (NK) cells cytotoxic T cells helper T cells plasma cells pre-T cells when a body cell presents a viral protein fragment coupled with MHC-1, which type of cell is most likely to recognize it? CD4 T cell CD8 T cell antigen-presenting cell (APC) B cell plasma cell An exogenous antigen that has been processed and presented displayed on the plasma membrane of an APC with MHC-II displayed on the plasma membrane a CD4 T cell with MHC-I a signal the immunological threat has been eliminated from the body a signal the cell has become cancerous a signal that there are bacteria living inside the cell

Explanation / Answer

2. E. cytolysis of microbial invaders- the activated complement proteins forms a transmembrane channel causing osmotic lysis of microbial invaders and microbial attack complex (MAC)

costimulation of B cells- when microbes invade and activate the complement system all the degradation and binding leads to activation of B cell towards the microbial antigen

3. A. NK cells and B. cytotoxic T cells

Activity of both NK cells and cytotoxic T cells is comparable in the immune system. They naturally recognise the microbial pathogen in the body even those without its MHC-I marker skipped by other immune cells and hence helps in fighting all the pathogens.

4. B. CD8-Tcell and E. plasma cell

MHC-I is a heterodimer consisting of two chains. During interaction, its alpha-chain spans the plasma membrane and interacts with the CD8-Tcells.

5. displayed on the plasma membrane of an APC with MHC-II

Specialised antigen presenting cells (MHC-II) presents the peptides that are derived from the endocytosed proteins by the cell. This process is called the exogenous pathway.

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