Part A A functioning adenoma of the lactotrophs, which are the cells that secret
ID: 176840 • Letter: P
Question
Part A
A functioning adenoma of the lactotrophs, which are the cells that secrete prolactin, may be treated with a drug that is the same as prolactin inhibiting hormone; that drug is __________.
Part B
The anterior pituitary hormones are water-soluble peptides, therefore they _________ a carrier protein.
Part C
Since the anterior pituitary hormones are water-soluble, their target cell receptors are located __________.
inside the Golgi
Part D
A MRI is a radiological tool that best looks at soft tissues; a regular X-ray and CT scan view hard tissues better. If a physician wishes to view the pituitary gland itself, it is best to use a __________; if the physician wishes to view the sella turcica, bone encasing the pituitary gland, it is best to use the __________.
CT scan; MRI
Part D
Cortisol and insulin have __________ effects on blood glucose level..
no
Part E
Pituitary microadenomas are less than 1 cm in diameter. Most functioning pituitary adenomas are microadenomas. A very small functioning microadenoma of the pituitary, that does not compress surrounding structures, may be most likely initially treated __________.
TSH ACTH TRH dopamineExplanation / Answer
Please find the answers below:
Part 1: Choic D (Dopamine is an antagonist of prolactin secretion and performs this prolactin inhibitor hormone-like function. Dopamine thus remains the most effective and pioneer biomolecule which prevents prolactin secretion from anterior lobe of pituitary. It also affects the pathophysiological state of somatomammot adenema)
Part 2: Choice A (The molecules, even hormones which are water soluble in nature do not require any carrier molecule to carry and transport them from one location to another in the body. The water soluble peptide hormones dissolve in plasma and are frequently transported to their target location)
Part 3: Choice C (The plasma membrane is a lipid bilayer by structure and allows only lipid-based hydrophobic molecules to pass through. Although peptide hormones are water soluble, but their structure is large enough which does not allow them to freely pass through the plasma membrane. Thus, these hormones have receptors present on the surface of cell membrane.)
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