The following are examples of large-scale DNA changes in an organism EXCEPT: Tra

Question

The following are examples of large-scale DNA changes in an organism EXCEPT: Transduction Transduction Point mutation Conjugation Recombination The features are requirement(s) for homologous recombination to occur: Very similar (homologous) DNA sequences are required. The site of exchange can be anywhere in the homologous sequences. Nucleotide sequences do not alter at the site of exchange. Enzymes are required to cut both strands of the double helix. All of the above. The lactose model is based on gene regulation that supports mechanism Activator mechanism Repressor mechanism Allosteric mechanism None of the above A DNA capable of inserting into genome (transposon) typically contains: Transposase gene AmpRgene TetR gene All of the above SCID in humans Is associated with mutation in Hemoglobin Adenosine Diaminase p53 ras The following type of mutation in a proto-oncogene may cause cancer in human: Translocation of gene Gene amplification Point mu

Explanation / Answer

32) C Point mutation, This is a change in single nucleotide difference which cause change in expression, when compared to other this small change, Transformation which refers the transfer od DNA from donor to recepient, conjugation of exchage of entire copy of plasmid through cinjugation tube, transduction transfer of genetic material through bacteriophage, recombination exchange of two DNA strands shows varaitibility,seggregation and ssortment.

33) E all of the above, when exchange of the chromosomes of DNA through out, identical or similar strand to repair the breaks or missed sequences is termed as homologous chromosomal recombination, for this enzymes are essential for cut and ligated the strands in recombination.

34) B repressor mechanism, Due to presence of lactose in the medium, which acts as inducer, repress the regulator proteins or repressor proteins so that trascription occurs, while in the absence of inducer repression occurs and transcription stopped or halted this is known as repressible operon system.

35)A transposase gene, these are called jumping genes, which flank a sequence involved non specific recmbination to facilitate this process between Ac and Ds elements the transposase enzyme which makes recombination by cutting and ligating into sequence shows varaibility of the DNA sequence. Barbara Mc clintock explains this theory of transposons in maize kernels.

36) B SCID in humans caused due to deficiency of ADA, popularily called as ADA SCID, Adenine deaminase Severe Combined Immunodefieciency syndrome, this is an example of Primary immuno defieciency, caused to due to accumulation of toxic metabolites in T and B cells, which leads to deficiency in immune response.

37) E all of the above,

Due to point mutation in the proto oncogene cause the changes in the gene expression which inturn converts into oncogenes, due to amplification high expression also causes the oncogene in cancer causing, translocation of genes also regulates the growth regulator gene,causes impaired expression.

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