Johnny goes to dental school to conduct research on Streptococcus mutans, a lead
ID: 176282 • Letter: J
Question
Johnny goes to dental school to conduct research on Streptococcus mutans, a leading cause of dental caries. What virulence factor is most important to its pathogenicity? How does diet contribute to virulence? Scientists will soon announce a vaccine against the microbe. Which class(es) of immunoglobulin(s) would be most important in combating "strep throat". If the bacterium is present on our teeth all the time, why do we not make antibodies to it naturally? Would protection due to this vaccine be naturally-acquired active immunity? Explain your answer.Explanation / Answer
The WapA gene in S. mutans is the most important for pathogenecity of this bacterium. Its expression helps in biofilm formation whixh results into more adhesion.
Diet is also very important virulence factor. In this, frequently meal consumption is more important and the other is the diet full of high carbohydrate (glucose, sucrose, and fructose)
Immunoglobulin class G (IgG) is the most important treatment for strep throat by immunoglobulin therapy.
The body makes antibodies against this bacterium but when bacterium gets contact with blood. The regular presence of bacterium with high concentration makes immunity weak and then causes the disease. Also the disease happens to those who have loss or of IgG production or less production.
No naturally acquired it is artificially acquired, in case of vaccination.
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