1- To treat your infection, your doctor prescribes an antibiotic. This antibioti

Question

1- To treat your infection, your doctor prescribes an antibiotic. This antibiotic inhibits the movement of a tRNA from the P-site to the E-site. Which step of translation does the antibiotic inhibit?

a- Amino acid entry

Peptidyl transfer

c- Translocation

d- Ribosome assembly

2- The antibiotic binds reversibly to an allosteric site on the ribosome. Which of the following will be occur as a result of this inhibitor?

a- Vmax will go up

b- Vmax will go down

c- Km will go up

Km will go down

a- Amino acid entry

Peptidyl transfer

c- Translocation

d- Ribosome assembly

Explanation / Answer

a. Amino Acid entry

Because during elongation, the tRNA brings the amino acids to the ribosomes. This antibiotic inhibits the movement of tRNA.

b. Vmax will go down

Because the binding of inhibitor will slow down the catalysis.

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