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So I found the answer to the question but I don\'t get it. Does this mean the gr

ID: 176096 • Letter: S

Question


So I found the answer to the question but I don't get it. Does this mean the graft was successful? A 32-year-old woman was treated for mantle cell lymphoma with a nonmyeloablative bone marrow transplant. Before the transplant and after a donor was selected, STR analysis was performed on the donor and the recipient to find informative alleles. One hundred days after the transplant, engraftment was evaluated using the selected STR alleles. The results from one marker, D5S818, are shown in the top panel. One year later, the patient was reevaluated. The results from the same marker are shown in the bottom panel. Results from engraftment analysis at 100 days (top) and 1 year (bottom) showing marker D5S818. R. recipient; D, donor Was the woman successfully engrafted with donor cells? Explain your answer.

Explanation / Answer

No, the graft was not succesfull because the STR allele 61188 of the donor is not expressed in recipient post transplant at 100 days or 1 year.

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