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17.You have identified a novel protein that localizes to the Golgi apparatus. Yo

ID: 17542 • Letter: 1

Question

17.You have identified a novel protein that localizes to the Golgi apparatus. You do not know whether this protein is a peripheral or a transmembrane protein. You therefore analyze the primary amino acid sequence (listed in the three letter code) for the presence of a transmembrane domain.

Met - Asp - Leu - Lys - Ile - Pro - Gly - Val - Glu - Arg - Met - Phe - Leu - Ile - Ser - Lys - Gly - Thr - Asp - Tyr - His - Asn - Gln - Val - Met - Val - Gly - Pro - Asp - Glu - Ala - Ala - Ala - Val - Met - Trp - Cys - Met - Phe - Ile - Val - Val - Val - Thr - Val - Glu - Glu - Gly - Asp - Met - Val - Ala - Ile - Ile - Val - Leu - Pro - Lys - Arg - Trp - Tyr - Phe - Ala - Gln - Tyr - Ala - Val - Leu - Ile - Leu - Met - Ala - Trp - Leu - Val - Phe - Val - Ile - Leu - Ala - Arg - Lys - His - Ala - Val - Ile - Leu - Trp - Tyr - Ala - Gly - Gln - Gly - Asn - Arg - His - Cys - Lys - Met

How many potential transmembrane domains can you identify in this protein?

Explanation / Answer

23 potential transmembrane domains

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