1. Which of the following is essential for conversion of the O to the L state du
ID: 175414 • Letter: 1
Question
1. Which of the following is essential for conversion of the O to the L state during chemiosmosis?
2. Which of the following is essential for supply of ADP to the matrix and when knocked out genetically leads to a rise in ROS levels in muscle cells?
3. Which of the following requires transamination and when inhibited has NO effect on hyperglycemic induction of endothelial cell ROS generation?
4. Which of the following inhibits complex I of the ETS and increases ROS generation in hyperglycemic endothelial cells?
5. Which of the following inhibits complex II and eliminates ROS generation in response to hyperglycemia in endothelial cells?
6. Which of the following directly decreases ROS?
7. What relieves oxidative stress in hyperglycemic endothelial cells by supplying H + to complex II?
8. Which of the following increases ROS by backing up ETS at complex III?
ADP
TTFA
Antiporter
antimycinA
Rotenone
UCP
SOD
Malate/aspartate shuttle
ADP
TTFA
Antiporter
antimycinA
Rotenone
UCP
SOD
Malate/aspartate shuttle
Explanation / Answer
1. ADP is essential for conversion of the O to the L state during chemiosmosis
2. Antiporter is essential for supply of ADP to the matrix and when knocked out genetically leads to a rise in ROS levels in muscle cells
3. Malate/aspartate shuttle requires transamination and when inhibited has NO effect on hyperglycemic induction of endothelial cell ROS generation
4. Rotenone inhibits complex of electron transport system at NADH dehydrogenase and prevent NADH oxidation and increases ROS generation.
5. TTFA inhibits complex II and eliminates ROS generation.
6. ADP directly decreases ROS.
7. Uncoupling proteins (UCP) relieves oxidative stress by supplying H+ to complex II.
8. Antimycin A increases ROS by backing up ETS at complex III.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.