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During October through December 2015, three research and development workers in

ID: 175056 • Letter: D

Question

During October through December 2015, three research and development workers in a company that makes metallic inks in Whoosits, Indiana, were seen in an outpatient clinic of the Indiana University Hospital complaining of cough, with "post nasal drip" and flushing of the face daily. She denied any wheezing. Additionally she experienced skin reactions to earrings and her belt buckle that she was previously able to wear without any reactions These items were not pure gold and were made from metal amalgams. All three employees worked in the same area in the factory where they had no symptoms doing work that involved formulating polymers and making coatings, nor when working in the same laboratory with metal plating baths They started on a new project that involved making formulations involving micron-sized silver particles for inks. What further questions might you want to ask? What sources of information might you use? What body system(s) might be affected by this exposure? What do you think the material is and why do you think that? What tests might you ask a physician to run to help you determine possible exposure? How would you protect future employees in this facility that makes these ink formulations?

Explanation / Answer

1. I would ask if there has been a history of any allergey in the patients or if they are taking any medications.

2. Respiratory system and nervous system are most likely to be affected.

3. The material is most likely to be nanoparticle of size less than 100 micrometre as they can easily penetrate the physical barriers and produce adverse effects on the body.

4. One could use aerosol sampler to detect the presence of nanoparticles in the body.

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