Next generation sequencing (NGS) methods are beginning to be used in ancient DNA

Question

Next generation sequencing (NGS) methods are beginning to be used in ancient DNA analyses. Which TWO of the following six statements are correct?
Choose at least one answer.
a. NGS allows better estimation of the amount of damaged DNA in a sample
b. Because NGS methods generally give short sequence lengths, they are not suitable for ancient DNA
c. NGS approaches are too expensive to use in ancient DNA projects
d. Bacterial cloning is still seen as the "gold standard" for ancient DNA analyses
e. Many ancient DNA extraction methods are not compatible with NGS techniques.
f. NGS methods can show DNA contamination, which is useful for ancient DNA projects

Explanation / Answer

b. Because NGS methods generally give short sequence lengths, they are not suitable for ancient DNA e. Many ancient DNA extraction methods are not compatible with NGS techniques.

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