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GIVEN: The fluid within a living cell is rich inpotassium chloride, while the fl

ID: 1740117 • Letter: G

Question

GIVEN: The fluid within a living cell is rich inpotassium chloride, while the fluid outside it predominantlycontains sodium chloride. The membrane of a resting cell is farmore permeable to ions of potassium than sodium, and so there is atransport out of positive ions, leaving the cell interior negative.The result is a voltage of about -75.5mV across the membrane,called the resting potential. If the membrane is6.95nm thick, and assuming the electricfield E across it is constant, (1.)determine themagnitude of E.

(2.)The membrane may be thought of as acapacitor: 2 charged surfaces filled with oil (dielectricconstant=2.94). Find its capacitance per unit area.


(3.)What is the restingmembrane's surface charge density?


(4.)Assume that themembrane's cytoplasmic (interior of cell) charge can be attributedto the presence of a certain fraction of negatively chargedphospholipid molecules, each with a cross-sectional area of0.555nm2. If each negatively charged lipid carries-1.60×1019C, how many such molecules arefound in 1.0m2 of the inner surface of themembrane?


(5.)What percentage of themembrane's inner surface do these molecules cover?


GIVEN: The fluid within a living cell is rich inpotassium chloride, while the fluid outside it predominantlycontains sodium chloride. The membrane of a resting cell is farmore permeable to ions of potassium than sodium, and so there is atransport out of positive ions, leaving the cell interior negative.The result is a voltage of about -75.5mV across the membrane,called the resting potential. If the membrane is6.95nm thick, and assuming the electricfield E across it is constant, (1.)determine themagnitude of E.

(2.)The membrane may be thought of as acapacitor: 2 charged surfaces filled with oil (dielectricconstant=2.94). Find its capacitance per unit area.


(3.)What is the restingmembrane's surface charge density?


(4.)Assume that themembrane's cytoplasmic (interior of cell) charge can be attributedto the presence of a certain fraction of negatively chargedphospholipid molecules, each with a cross-sectional area of0.555nm2. If each negatively charged lipid carries-1.60×1019C, how many such molecules arefound in 1.0m2 of the inner surface of themembrane?


(5.)What percentage of themembrane's inner surface do these molecules cover?


Explanation / Answer

a) Formula for calculating the value of the magnitude of theelectric field is                       E = V / d                          = (75.5mV) / (6.95nm)                          = (75.5*10-3V) / (6.95*10-9m)                          = 10.86*106 V/m b) We know the formula for the capacitance with dielectric isplaced in the between the plates of the capacitor is               C = kAo / d               C/A = ko / d   ......................(1) Here k = 2.94         o =8.85*10-12C2/N.m2          d =6.95*10-9m c) Formula for calculating the value of the surface chargedensity is             = Eo               = (10.86*106V/m)(8.85*10-12C2/N.m2)               = (10.86*106V/m)(8.85*10-12C2/N.m2)