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You have identified various tRNAs from a variety of hypothetical orgainisms. Giv

ID: 171209 • Letter: Y

Question

You have identified various tRNAs from a variety of hypothetical orgainisms. Given the anticodon of the tRNA, determine if each tRNA individually could conform to the nearly universal genetic code. Assume that the tRNA in question can only be charged with one amino acid and it is the same amino acid everytime. If the tRNA is not intended to be charged with an amino acid, it can never be charged with an amino acid.

7. Anticodon: 3' A C U 5'

Could this tRNA conform to the nearly universal genetic code?

Select one:

Yes

No

8. Anticodon: 3' U C I 5'

Could this tRNA conform to the nearly universal genetic code?

Select one:

Yes

No

Explanation / Answer

1. If anticodon = 3' ACU5', the codon would be 5'UGA3'. This is one of the STOP codons in the universal genetic code, and so there is not normally a tRNA with that anticodon. No, it will not conform the nearly universal genetic code.

2. If anticodon= 3' UCI 5', Of course, UCA can base-pair with a codon specified by AGU. The UCA anticodon would be converted to UCI post-transcriptionally. Due to wobble (and deamination), a UCA could also pair with AGA and insert the wrong AA (Arg not Ser). This would be bad. For this reason, UCA/UCI anticodon does not exist. So, the answer is No.

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