Question 22 Deposition: Duke Energy and Gov. McCrory ignored cancer-risk estimat

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Question 22

Deposition: Duke Energy and Gov. McCrory ignored cancer-risk estimate for polluted well water approved by CDC Winston Salem Journal - June 9, 2016 http://www.iournalnow.com/news/local/deposition-duke-energy-and-gov-mccrorv-ignored-cancer-risk-estimate/article 85fce9cb-22cl-538d-ab8d-2689942cd98f.html ... "The screening level must carry a lifetime cancer risk of 1 in 1 million. Ideally, water should contain no hexavalent chromium, environmental advocates say, but the level of 0.07 parts per billion is considered health-protective. Well owners such as Amy Brown in Belmont, near Duke Energy's Allen power plant, would face a lifetime cancer risk of 1 in 1 million if the concentration of hexavalent chromium met that level. The chances would be even slimmer if the concentration were smaller." To make the calculations, what two values are needed to calculate incremental risk? __________ You have to drink the water to get exposed. So, what is being assumed about that process, and for how long? ________________ You work in a building for 10 years and develop asthma. Is this a chronic or acute effect? 100 additional cancers of some type were observed over course of peoples' lifetime in a population of 5 million. Everyone had the same exposure to the causative chemical, in units of mg/kg-day. What is the ILCR for the chemical and that cancer? The NOAEL concentration for a chemical in air for chronic exposure for some endpoint is 0.1 mu g/m^3. What will be selected as the reference dose concentration for inhalation? For the same chemical in the preceding problem, the measured exposure concentration is 0.05 mu g/m^3. What is the Hazard Quotient?

Explanation / Answer

When a certain causative chemical has been exposed to a long time it has effects on ones life.

ILCR i.e, incremental lifetime cancer risk depends directly on the following factors.

1.Concentration of the chemical exposed.

2. Intake rate of the contaminated environmental medium forthe age 'n'.

3. Exposed duration.

4. Cancer slope rate.

This all factors directly affects the people drinking that water and so can be said that ILCR is higher.

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