c Biology question chegg.cc Lo Quiz: Problem Set 5 E Guide-to-Cover-Letters pdf

Question

c Biology question chegg.cc Lo Quiz: Problem Set 5 E Guide-to-Cover-Letters pdf CX lecture notes and additiona Problem Set 5.pdf X O file:/// C/Users/xM arous7/Downloads/Problem9620Set 6205.pdf A 4 month old infant was brought to the clinic because she exhibited poor muscle tone and had difficulty feeding. Laboratory analysis of organic acids in her urine gave the following results. Data are presented as mmol/mol creatinine. compound normal range atient 26.2 680 720 citrate 720 10-12 fumarate 1750 95 115 lactate 1.1 35 42 malate 160 200 succinate 3700 Based on these data, identify the enzyme that is deficient in the infant from the list below a Ask me anything 3:38 PM 3/21/2017

Explanation / Answer

Fumarase

because there is dificiency of Citrate and Malate is observed in the infant it means the conversion fumarate to malate is disturbed which is done by fumarese the deficiency of Malate will lead to oxaloacetate deficiency which finally affect the citrate availability.

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