C chegg study Guided Lo Quiz: Problem Set 5 solut E Guide-to-cover-Letters pdf O
ID: 170137 • Letter: C
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C chegg study Guided Lo Quiz: Problem Set 5 solut E Guide-to-cover-Letters pdf O lecture notes and additiona Problem set 5.pd x O file:/// C/Users/xM xMarcus7x/Downloads/Problem%20set%205.pdf Consider acetylCoA labeled with 4C at the methyl carbon of the acetyl group. How many carbons are labeled in isocitrate in round 1? Select How many carbons are labeled in a ketoglutarate in round 1? SeleeH How many carbons are labeled in oAA in round 1? Select h How many carbons are labeled in rate in round 2? Select How many carbons are labeled in a ketoglutarate in round 2? Select Select How many carbons are labeled in OAA in round 2? Question 11 1 pts a Ask me anything 3:35 PM 3/21/2017Explanation / Answer
Acetyl CoA molecule is labelled with 14C at methylated carbon and the labelled carbon appears in products of TCA cycle.
During round 1, the labelled carbon appears in one carbon of isocitrate, a C6 molecule; 14C appears in 2 carbons of alphaketoglutarate, C5 molecule. In OAA 14C appears in 1 carbon only. OAA is a C4 molecule.
During round 2, the labelled carbon appears in 2 carbons of isocitrate, a C6 molecule; 14C appears in 2 carbons of alphaketoglutarate, C5 molecule. In OAA, C4 molecule the 14C appears in 1 carbon only.
11. The labelled 14C of methylated carbon of acetyl CoA molecule appears in the products of TCA cycle during conversion of isocitrate into alphaketoglutarate. Therefore, 14CO2 appears in round 1. Option 1 is correct.
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