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If a combination of genetic and environmental factors determines a particular hu

ID: 167819 • Letter: I

Question

If a combination of genetic and environmental factors determines a particular human trait, one should observe which of the following from twin studies? some concordance between dizygotic twins and a lower concordance between monozygotic twins some concordance between monozygotic twins and a lower concordance between dizygotic twins a similarly low or high concordance between both monozygotic and dizygotic twins 100% concordance between dizygotic twins and no concordance between monozygotic twins None of the above What is the most likely mode of inheritance for the pedigree shown above? autosomal dominant autosomal recessive X-linked dominant X-linked recessive Y-linked

Explanation / Answer

22. Some concordance between monozygotic twins and a lower concordance between dizygotic twins. Because monozygotic twins are from same zygote which means that it shares same genetic information.

23. X-linked dominant.

Square represents male and Circle represents female.

Male has one X and One Y but female with two XX

In the second generation, daughters are affected so one X from father (affected) and other X from mother (Not affected). Only if the affected X is dominant, daughters will be affected. X cannot be recessive which needs both X to be affected.

In the third generation, two son and a daughter is affected. So sons will have one affected X from father which is dominant.

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