In both prokaryotes and eukaryotes, initiation of translation usually begins imm
ID: 166711 • Letter: I
Question
In both prokaryotes and eukaryotes, initiation of translation usually
begins immediately upstream of a Shine-Dalgarno sequence.
requires the action of release factors, which cause the small and large subunits of a ribosome to associate with one another.
requires the action of initiation factors.
begins at a UAG codon downstream of the 5’ UTR of an mRNA molecule.
begins only after ubiquitin has been added to the mRNA molecule to be translated.
A.begins immediately upstream of a Shine-Dalgarno sequence.
B.requires the action of release factors, which cause the small and large subunits of a ribosome to associate with one another.
C.requires the action of initiation factors.
D.begins at a UAG codon downstream of the 5’ UTR of an mRNA molecule.
E.begins only after ubiquitin has been added to the mRNA molecule to be translated.
Explanation / Answer
Choice C is correct.
Reason: Translation of protein in both prokaryotes and eukaryotes require a comprehensive activation of various initiation factors (with respective eukaryotic and prokaryotic isoforms). These initiation factors are involved in modulating the translation process by recruiting various components of the translational machinery in the cells. These are essentially present in both eukaryotes and prokaryotes. Majorly, three classes of initiation factors are found in both prokaryotes and eukaryotes which have nearly similar functions. In absence of these initaition factors, the ribosomal subunits will not bind to each other and hence, no translation will take place.
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