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Select the two true statements about signal transduction from the statements bel

ID: 164283 • Letter: S

Question

Select the two true statements about signal transduction from the statements below.

1. Galpha proteins are active in the GTP-bound state.

2. First messengers must be transported into the cells to initiate signal transduction.

3. Ligand binding causes conformational changes in G-protein coupled receptors that result in changes in the receptor’s enzymatic activity.

4. Either phosphodiesterase or phospholipase C can act as a second messenger in signal transduction processes.

5. Interactions of Galpha with other proteins, such as adenylate cyclase, can affect their enzymatic activity.

1. Galpha proteins are active in the GTP-bound state.

2. First messengers must be transported into the cells to initiate signal transduction.

3. Ligand binding causes conformational changes in G-protein coupled receptors that result in changes in the receptor’s enzymatic activity.

4. Either phosphodiesterase or phospholipase C can act as a second messenger in signal transduction processes.

5. Interactions of Galpha with other proteins, such as adenylate cyclase, can affect their enzymatic activity.

Explanation / Answer

The two true statements about signal transduction from the statements are-

1. G-alpha proteins are active in the GTP-bound state.

5. Interactions of G-alpha with other proteins, such as adenylate cyclase, can affect their enzymatic activity.

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