1. What is a cyclin-dependent kinase and how is it thought to work? (Answer not

Question

1. What is a cyclin-dependent kinase and how is it thought to work? (Answer not found in article – see your text book or my lecture.)

2. Why was Heinemann’s hypothesis that a metabolic oscillator might set the pace for cell division a good bet? (Hint: What does a cell need to carry out cellular work?)

3. Why was Heinemann’s choice of NADH and ATP as indicators of the metabolic oscillators an appropriate choice?

4. Under what conditions are the metabolic and cell-cycle oscillators coupled? When are they uncoupled?

To see the original article click here. ( http://www.sciencedirect.com/science/article/pii/S1097276516307262 )

Explanation / Answer

Ques-1:

1. What is a cyclin-dependent kinase and how is it thought to work? (Answer not found in article – see your text book or my lecture.)

Answer:

Cyclin-dependent kinase is an enzyme that promote cell cycle during somatic cell division or interphase of mitosis. A single cyclin dependent kinase protein is going to bind predominantly to all classes of cyclins that enable entire cell-cycle process by further altering cyclin proteins at various stages of the cell cycle

Specific steps in cell cycle are controlled by cyclines, which act through cyclin dependent kinases (CDKs). Cyclins are the regulatory proteins to which the cyclin dependent kinases (CDKs) bind and activate the CDKs.

Related Questions

Navigate

• Browse (All)
• Browse 1
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.