Data are provided below for two different populations. For each of these populat

Question

Data are provided below for two different populations. For each of these populations, calculate the frequencies for the other three haploid genotypes (Ab, aB, and ab) and the linkage disequilibrium coefficient (D). Also, for each of the four haploid genotypes in the population, state whether it occurs with more, less, or the same frequency as you would expect at random given the allele frequencies [no further explanation is required]: i. F(AB) = 0.49; F(A) = 0.5; F(B) = 0.7 ii. F(AB) = 0.16; F(A) = 0.2; F(B) = 0.8

Explanation / Answer

for first population, the frequencies for three haploid genotypes:

F(A) = 0.5 then F(a) = 0.5 (As p + q = 1)

F(B) = 0.7 then F(b) = 0.3

therefore F(Ab) =0.15, F(aB) = 0.35, F(ab) = 0.15

and disequibrium coefficient:

DAB = pAB - pA pB

For 2nd population. the frequency for the haploid genotype:

F(A) = 0.2 then F(a) = 0.8

F(B) = 0.8 then F(b) = 0.2

therefore F(Ab) = 0.16, F(aB) = 0.16, F(ab) = 0.16

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