1. Unlike Ebola virus, SARS virus a. has large spikes that look like a “crown”.
ID: 15921 • Letter: 1
Question
1. Unlike Ebola virus, SARS virusa. has large spikes that look like a “crown”.
b. is enveloped.
c. is helical.
d. is in the family Togaviridae.
e. is a ssRNA virus.
2. Which virus or virus family is described in the following passage?
Electron micrographs of the hemagglutinin subunits (in the presence of SDS) showed
rods approximately 40 Å wide and 140 Å long. The neuraminidase subunits had a quite
different appearance. In the presence of SDS, these were seen as oblong structures about 85 Å long and 50 Å wide with a centrally attached fibre 100 Å long possessing what appeared to be a diffuse tail or small knob about 40 Å in diameter at its end.1
a. Togaviridae
b. Epstein-Barr virus
c. Smallpox virus
d. Orthomyxoviridae
e. Filoviridae
f. Rabies virus
3-Following is a passage from the New England Journal of Medicine:
______________________ is an exclusively human herpesvirus that ... becomes latent in
cranial-nerve and dorsal-root ganglia, and frequently reactivates decades later to produce shingles and postherpetic neuralgia. In immunocompetent elderly persons or
immunocompromised patients, ____________________ may produce disease of the central nervous system.
This passage refers to which virus?
a. West Nile virus
b. Smallpox virus
c. Epstein-Barr virus
d. Ebola virus
e. Varicella-zoster virus
4. Pneumoviruses can cause colds and pneumonia in humans. They are single-stranded,
negative-sense, nonsegmented RNA viruses. These enveloped viruses are surrounded by an envelope that is characterized by fusion glycoproteins and host-derived proteins. With this knowledge, it is likely that pneumoviruses
a. enter host cells via endocytosis.
b. leave host cells by budding.
c. enter host cells via membrane fusion.
d. A and B
e. B and C
5. Recall that poliovirus is a positive-sense (+) ssRNA virus. The 5’ à? 3’ strand of RNA,
once uncoating has taken place, can serve as an mRNA and encode for viral proteins.
However, in order for the virus to create more +ssRNA to package in daughter viruses, it must
a. generate a dsRNA molecule that can encode for the synthesis of more +RNA.
b. integrate into the host cell DNA.
c. utilize an RNA-dependent DNA polymerase to make a heteroduplex.
d. undergo reassortment
e. All of the above
6. Some influenza hosts, such as humans and pigs, can simultaneously contract human,
avian and swine influenza viruses at the same time. What can occur during the maturation phase of virus replication in such a host?
a. Reassortment
b. RNA of all three sources: human, swine and avian, can be packaged into a single
virion.
c. Genetic shift
d. All of the above
7. The HIV virion contains enzymes/proteins that do all of the following EXCEPT
a. An enzyme that creates –DNA using +RNA as template.
b. A protein that serves as a chemokine receptor.
c. A DNA-dependent DNA polymerase.
d. An enzyme that allows +/- viral DNA to be spliced into the host cell’s DNA.
e. A protein that mediates membrane fusion.
8. After a long series of biochemical tests, Kyle and Matt were finally able to identify their Gram-negative unknowns as Pseudomonas aeruginosa and Shigella dysenteriae,
respectively. As they compare notes, they realize that their unknowns are in the
___________ Pseudomonadaceae and Enterobacteriaceae, respectively. However, they also note that both of their unknowns are in the ______________ ? proteobacteria.
a. genera, species
b. phyla, family
c. families, class
d. order, phyla
e. classes, order
9-Hydrogenobaculum acidophilum is a resident of Yellowstone’s Norris Geyser basin. This thermoacidophilic microbe grows in stringy, white mats and is a member of the phylum Aquificae. Hydrogenobaculum acidophilum
a. could be further researched in Volume 2 of Bergey’s Manual of Systematic
Bacteriology.
b. is in the domain Archaea.
c. is a deeply branching bacterium.
d. is a proteobacterium.
e. All of the above
10-After talking about the Group A Streptococci (GAS) and their capability to sometimes cause a flesh-eating disease called necrotizing fasciitis, Derek decides to research this group a bit more. As he reads, he quickly learns that
a. they are microaerophilic Gram-negative rods.
b. they are in the phylum ?-proteobacteria.
c. they are found Volume 4 of Bergey’s Manual of Systematic Bacteriology.
d. they have less than 50 mol % GC content.
e. none of the above
Explanation / Answer
1. Unlike Ebola virus, SARS virus
a. has large spikes that look like a “crown”.
2. Which virus or virus family is described in the following passage?
Electron micrographs of the hemagglutinin subunits (in the presence of SDS) showed
rods approximately 40 Å wide and 140 Å long. The neuraminidase subunits had a quite
different appearance. In the presence of SDS, these were seen as oblong structures about 85 Å long and 50 Å wide with a centrally attached fibre 100 Å long possessing what appeared to be a diffuse tail or small knob about 40 Å in diameter at its end.1
a. Togaviridae
b. Epstein-Barr virus
c. Smallpox virus
d. Orthomyxoviridae
e. Filoviridae
f. Rabies virus
3-Following is a passage from the New England Journal of Medicine:
______________________ is an exclusively human herpesvirus that ... becomes latent in
cranial-nerve and dorsal-root ganglia, and frequently reactivates decades later to produce shingles and postherpetic neuralgia. In immunocompetent elderly persons or
immunocompromised patients, ____________________ may produce disease of the central nervous system.
This passage refers to which virus?
e. Varicella-zoster virus
4. Pneumoviruses can cause colds and pneumonia in humans. They are single-stranded,
negative-sense, nonsegmented RNA viruses. These enveloped viruses are surrounded by an envelope that is characterized by fusion glycoproteins and host-derived proteins. With this knowledge, it is likely that pneumoviruses
d. A and B
5. Recall that poliovirus is a positive-sense (+) ssRNA virus. The 5’ à? 3’ strand of RNA,
once uncoating has taken place, can serve as an mRNA and encode for viral proteins.
However, in order for the virus to create more +ssRNA to package in daughter viruses, it must
a. generate a dsRNA molecule that can encode for the synthesis of more +RNA.
b. integrate into the host cell DNA.
c. utilize an RNA-dependent DNA polymerase to make a heteroduplex.
d. undergo reassortment
e. All of the above
6. Some influenza hosts, such as humans and pigs, can simultaneously contract human,
avian and swine influenza viruses at the same time. What can occur during the maturation phase of virus replication in such a host?
a. Reassortment
b. RNA of all three sources: human, swine and avian, can be packaged into a single
virion.
c. Genetic shift
d. All of the above
7. The HIV virion contains enzymes/proteins that do all of the following EXCEPT
a. An enzyme that creates –DNA using +RNA as template.
b. A protein that serves as a chemokine receptor.
c. A DNA-dependent DNA polymerase.
d. An enzyme that allows +/- viral DNA to be spliced into the host cell’s DNA.
e. A protein that mediates membrane fusion.
8. After a long series of biochemical tests, Kyle and Matt were finally able to identify their Gram-negative unknowns as Pseudomonas aeruginosa and Shigella dysenteriae,
respectively. As they compare notes, they realize that their unknowns are in the
___________ Pseudomonadaceae and Enterobacteriaceae, respectively. However, they also note that both of their unknowns are in the ______________ ? proteobacteria.
a. genera, species
b. phyla, family
c. families, class
d. order, phyla
e. classes, order
9-Hydrogenobaculum acidophilum is a resident of Yellowstone’s Norris Geyser basin. This thermoacidophilic microbe grows in stringy, white mats and is a member of the phylum Aquificae. Hydrogenobaculum acidophilum
a. could be further researched in Volume 2 of Bergey’s Manual of Systematic
Bacteriology.
b. is in the domain Archaea.
c. is a deeply branching bacterium.
d. is a proteobacterium.
e. All of the above
10-After talking about the Group A Streptococci (GAS) and their capability to sometimes cause a flesh-eating disease called necrotizing fasciitis, Derek decides to research this group a bit more. As he reads, he quickly learns that
a. they are microaerophilic Gram-negative rods.
b. they are in the phylum ?-proteobacteria.
c. they are found Volume 4 of Bergey’s Manual of Systematic Bacteriology.
d. they have less than 50 mol % GC content.
e. none of the a
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