3. The following set of experimental results relates the growth (+) of Neurospor

Question

3. The following set of experimental results relates the growth (+) of Neurospora on several media (MM = minimal medium without additives). The design is similar to that used by Beadle and Tatum in their classic experiments leading to the one-gene, one-enzyme statement. The letters A and B represent nutritional supplements; a plus (+) represents growth; and a minus (–) indicates no growth.
                                 Medium
                        Strain  MM   MM + A   MM + B
                        t409    -       +            +
                        t410    +       +            +
                        r3        -        -            +

Based on the data provided, select the correct statement:
A. Strain t409 is the wild-type strain, and the last substance in the pathway is B.
B. Strain t410 is the wild-type strain, and the last substance in the pathway is B.
C. Strain r3 is the wild-type strain, and the last substance in the pathway is B.
D. Strain t410 is the wild-type strain, and the last substance in the pathway is A.
E. Strain t410 is the wild-type strain, and the last substance in the pathway is MM

Explanation / Answer

The correct answer is E. The wild-type strain can grow in the most minimal media, which is MM, leading to t410 to be the wild-type strain. The last substance in the pathway is MM, which means the it can take the minimal nutrients yet still survive.

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