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1.Suppose you want to design an epidemiological study to understand the associat

ID: 154082 • Letter: 1

Question

1.Suppose you want to design an epidemiological study to understand the association between air pollution and birth effects (e.g., low birth weight, infant mortality, newborn blood pressure & heartrate) in Wayne County. What might be 2-3 challenges you face when attempting to effectively and accurately collect information or measure the exposure (i.e., air pollution)? What might be 2-3 challenges you face when attempting to effectively and accurately collect information or measure the health outcomes (i.e., various birth effects)?

2. After reading the Marsa article, address this question in your own words: Why are geographic cancer clusters so hard to prove?

Explanation / Answer

2 challenges during measure pollution exposure: exposure bias and multicollinearity in multipollutant models( this is in reference to the regression models)

2 challenges during accurately measuring health outcomes: interrelationships between major endpoints( statistical modelling) and choice of appropriate exposure metrics..

The reason why cancer clusters are so hard to prove because of possibility of randomness, difference in duration of exposure and various people moving in and out of the area having different amounts of exposure