Two unrelated women each suffer from a complex disease where family, twin and ad
ID: 15388 • Letter: T
Question
Two unrelated women each suffer from a complex disease where family, twin and adoption data suggest that genetic susceptibility is important. The disease if twice as common in men as in women. Anne is the only affected person in her family; Betty's brother and son are affected. For each of the following four comparisons, decide for which ones the risk is higher.A. The risk of a son of Anne being affected, compared to the risk to a daughter of hers.
B. The risk of a daughter of Betty being affected, compared to the risk to a son of hers.
C. The risk Betty's next baby will be affected compared to the risk to Anne's next baby.
D. All of the above
Explanation / Answer
Two unrelated women each suffer from a complex disease where family, twin and adoption data suggest that genetic susceptibility is important. The disease if twice as common in men as in women. Anne is the only affected person in her family; Betty's brother and son are affected. For each of the following four comparisons, decide for which ones the risk is higher.
A. The risk of a son of Anne being affected, compared to the risk to a daughter of hers.
B. The risk of a daughter of Betty being affected, compared to the risk to a son of hers.
C. The risk Betty's next baby will be affected compared to the risk to Anne's next baby.
D. All of the above
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