The following are all false statements. Why? 1. When ionotropic channels open, n

Question

The following are all false statements. Why? 1. When ionotropic channels open, neurotransmitters can move in or out of the neuron 2. lons can bind to different sub-receptor types to create different changes in a neuron 3. The amplitude of an action potential depends on how much excitatory of inhibitory input a neuron receives 4. Blocking voltage-gated calcium channels would not lead to neurotransmitter release because calcium is needed to help neurotransmitters get packaged into vesicles. 5. Neurotransmitters are free to move in and out of neurons 6. If voltage gated sodium channels are blocked, an action potential can occur, but neurotransmitters will not be released into the synapse

Explanation / Answer

1) The first class of neurotransmitter receptors are ligand-activated ion channels( also known as ionotropic receptors). ionotropic receptors are large protein complexes.

Ligand-activated ion channels: These receptors are membrane-spanning ion channel proteins that unlock stright in reaction to ligand binding.

They have exact place that are binding sites for the neurotransmitter, as well as membrane-spanning section that form the channel. They face a change in shape when neurotransmitter binds and cause the channel to open. This may have either an excitatory or an inhibitory effect, depending on the ions it pass through the channel and their concentrations inside and outside the cell.

5) Ions are electrically charged particles. The protein membrane of a neuron function as a barrier to ions . Ions move over the membran through ions channels that open and close due to the pressence of neurotransmitter. when the concentration of ions inside the neurons changes . The electrical property of the membran change itself .Communication between neurons take place at synapses by the process of neurotransmission.

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