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This illustration is a very simplified, but clear depiction of UCP in mitochon-

ID: 151250 • Letter: T

Question

This illustration is a very simplified, but clear depiction of UCP in mitochon- dria. Familiarize yourself with this illus- tration and answer questions below. 5pts multiselect Part 2. Uncoupling protein 1 (UCP 1), also known as thermogenin is a proton channel found in the mito- chondrial innermembrane. UCP 1 is activated by a variety of different stimuli, including fatty acids, cold and neural activity. When stimulated to do so, these thermogenins allow for protons to return (actually a significant influx) to the matrix, down the concentration gradient (bypassing the ATP Synthetase), which generates a lot of heat for the cell, tissue, organ, and the organism What happens when you add/activate lots of UCP 1 to ATP synthesis and oxygen consumption

Explanation / Answer

what are molecules referred to as that save you the proton gradient from forming?
uncouplers

uncouplers reduce to rubble builds up of proton gradient so that ATP cannot be shaped with the aid of ATP synthase. this causes a lower in ATP within the cell and whilst the cell realizes this it increases the and so on to make greater electricity. while the and so forth is accelerated, oxygen intake goes up.

each inhibitor and uncouplers decrease ATP synthesis
and many others inhibitors lower and so on and o2 consumption. prevent a transfer of electrons
uncouplers increase and so on and o2 intake

how do uncouplers paintings?
they punch holes within the inner mitochondrial membrane and prevent a gradient from forming

why do uncouplers boom and many others and o2 consumption?
cell realizes ATP low and will increase and so on and o2 consumption to compensate

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