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13. The codon 5\' CAU 3\' specifies the amino acid histidine. A. What would be t

ID: 151092 • Letter: 1

Question

13. The codon 5' CAU 3' specifies the amino acid histidine. A. What would be the nucleotide sequence of the template DNA strand specifying this codon? Be sure to indicate directionality, here and in your answers to part B and C as well. B. What would be the nucleotide sequence of the non-template DNA strand? C. What would be the nucleotide sequence of the anticodon of the tRNA molecule that recognizes this codon? D. What point mutation in the DNA sequence would result in a codon specifying arginine, and would this point mutation be a transition or a transversion? Briefly explain. The standard genetic code table can be found on page 6 of the exam.

Explanation / Answer

Answer- (1) Nucleotide sequence in template strand is

3' GTA 5'

(2) Nucleotide sequence in non templte strand is 5' CAT 3'

(3) Nucleotide sequence in anticodon of tRNA is 3' GTA 5'

(4) since codon 5' CGU5 3' end at mRNA represent arginine terfore template strand for this will be 3' GCA 5' thus there is mutation at 2 nd nucleotide, Thymine is replaced by Cytosine in template strand.

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