This is an upper division college animal physiology class question: Explain the

Question

This is an upper division college animal physiology class question:

Explain the differences and similarities of ionotropic and metabatropic chemical synapse.

Please explain and give examples like how fast somthing is and relating it to the signal transduction pathway (like which steps are metabotropic or ionotropic

Signal Transduction Stimulus reaches receptor cells Receptor protein is activated Cascade of second messengers lon channels open (or close) Change in membrane potential Change in membrane potential Change in amount of transmitter spreads to spike initiating zone released by receptor cell r el Change in number or frequency of action potentials

Explanation / Answer

a. Ionotropic receptor: recognition site is located on the ion channel protein, reception binds to neurotransmitter and ion channels open (nicotinic)
i. DIRECT AND FAST
b. Metabotropic receptor: NO direct control over ion channel, recognition cite is extracellular, intracellular G Protein binds to neurotransmitter and separates from the receptor to open other ion channels or activate second messengers (muscarinic)
i. INDIRECT AND SLOW

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