BIO 2110 Genetics Homework 3, due 25 September 2018 Name 2. A single tRNA can be

Question

BIO 2110 Genetics Homework 3, due 25 September 2018 Name 2. A single tRNA can be used to read all of the codons for Isoleucine (lle). What would be the sequence, from 5' to 3', of the anticodon for this tRNA? What is the smallest number of tRNAs that would be required to read all of the codons for Arginine (Arg). What would be the sequences, from 5' to 3', of the anticodons of these tRNAs. What is the minimum number of amino-acyl tRNA synthetases that would be required to charge these tRNAs. Explain.

Explanation / Answer

1.Isoleucine has 3 codons ATT, ATC, ATA.

Anticodon sequence would be-

UAA , UAG, UAU

2. Arginine has 6 codons- CGT, CGC, CGA, CGG, AGA, AGG

Its anticodons are- GCA , GCG, GCU, GCC, UCU, UCC

Thus 6 t RNAs would be required.

tRNA (reading 3' to 5') has anticodons complementary to the codons in mRNA and can be "charged" covalently with amino acids at their 3' terminal.

In humans, the 20 different types of aa-tRNA are made by the 20 aminoacyl-tRNA synthetases, one for each amino acid of the genetic code. Thus in this case, only one type of aminoacyl synthetase is required. There is normally a single aminoacyl tRNA synthetase for each amino acid,

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