1. The human bone disease osteogenesis imperfecta is due to a dominant mutation
ID: 148500 • Letter: 1
Question
1. The human bone disease osteogenesis imperfecta is due to a dominant mutation that is incompletely penetrant in heterozygotes. The Penetrance value for this genotype is currently estimated to be 0.7. Two phenotypically normal individuals are heterozygous for this gene and considering starting a family. What is the probability that they will have an affected child?
0.30
0.40
0.60
0.70
0.75
2. In a disputed parentage case, a child is blood type A, while the mother is blood type B. What blood type could exclude a male from being the father?
O
B
B or AB
B and O
B, AB, or O
A, B or O
Explanation / Answer
2. when the mother blood group is B and the child Blood group is A his father's blood group should be A type.
so the answer here is option 5. ( B, AB or O) these blood groups cannot be a father of that child.
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