1. The accompanying pedigree and gel diagram show the molecular phenotypes obtai

Question

1. The accompanying pedigree and gel diagram show the molecular phenotypes obtained from genomic DNA samples. The bands are characteristic DNA fragments that distinguish two alleles of a single gene. Examine the bands for the males and females of each generation and answer the questions a. What mode of inheritance does the pedigree suggest? b. On the basis of this hypothesis, and using A1 to represent the allele associated with the 4-kb band and A2 to represent the allele associated with the 9-kb band, write the genotype of each individual in the pedigree I-2 Genotype -1 1-2 11-1 1l-2 1l-3 Il-4 1l-5 1l-6 12 kb 6 kb 3 kb 1 kb

Explanation / Answer

Genotype

I1- A2A2

I2- A1A1

II1- A2A2

II2- A1A2

II3- A2A2

II4- A2A2

II5- A1A2

II6- A1A1

III1- A1A1

III2- A1A2

III3- A1A2

III4- A2A2

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