1.What type of mature cell in a human could never undergo mitosis? 2.If you want
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Question
1.What type of mature cell in a human could never undergo mitosis?
2.If you wanted to prove that DNA but not RNA synthesis was preceeding, then what radioactive compound would you use?
3. Suppose that a person was exposed to a mutation-inducing chemical (i.e. a mutagen) so that many of the adenines in DNA are changed to appear to be guanines. How could that cause a problem?
4. Tetracyline prevents t-RNAs from delivering their amino acids to the usual destination. This action will prevent what type of synthesis from occurring?
5. Freckled skin is a dominant characteristic in humans. How is it that a freckled man and women have a non-freckled child?
Explanation / Answer
Following cells in humans doesn't go under mitosis:
1. Neurons: They lack centrioles and hence cannot perform mitosis. So nerve cells do not divide.
2. Cardiac muscles: the mammalian heart loses its regenerative potential soon after birth. Adult cardiac myocytes permanently exit the cell cycle, and when adult cardiac myocytes are subjected to a growth stimulus, they undergo an increase in cell size (hypertrophy) but do not proliferate.
3. Red Blood Cells: they do not divide as lack the nucleus.
4. White blood cells: white blood cells like granulocytes, macrophages, dendritic cells and natural killer cells are all terminally differentiated cells, hence don’t divide at all.
5. Skeletal muscles: The skeletal muscle fibres themselves, cannot divide. However, muscle fibres can lay down new protein and enlarge (hypertrophy).
6. Adipose cells: the adipose cells also do not divide due to constraint impart by the large Lipid droplets.
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