Insulin is a peptide therapeutic used to manage Type 1 diabetes, which affects m
ID: 147713 • Letter: I
Question
Insulin is a peptide therapeutic used to manage Type 1 diabetes, which affects more than 20 millior people worldwide according to the International Diabetes Federation. A significant limitation to the broad distribution and use of insulin to treat Type 1 diabetes is the fact that it must be administered by injection rather than orally. Why is insulin administered by injection and not orall? Insulin would be broken down in the mouth. Insulin cannot be made in a solid form (pills). Insulin would not survive transit through the stomach and gut environments. Part C Peptides typically carry that reduce transport across the core of the membrane bilayer. uncharged groups (i.e. some side chains) charged groups (i.e., N- or C-termini and some side chains) hydrophylic hydrophobicExplanation / Answer
1)Insulin in nit given orally beacuse it gets breakdown by the digestive juices in the gastrointestinal tract
2)uncharged,hydrophobic
3)reduce,more
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