12. Mary\'s father has ornithine transcarbamylase deficiency (OTD), an X-linked
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Question
12. Mary's father has ornithine transcarbamylase deficiency (OTD), an X-linked recessive disorder producing mental deterioration if not property treated. Mary's mother is homozygous for the no allele. a. What is Mary's genotype? (Use D to represent the dominant allele and d to represent the recessive allele- but remember to write them as X° and X* !) b.Ir Mary hasa son with a normal man, what is the chance that the son will have OTD? u (nenu c. If Mary has a daughter with a normal man, what is the chance the daughter will be a heterozygous d. Identify the genotype of a male with whom Mary could produce a daughter with OTD e. Draw the following pedigree, including genotypes for each individual: - Generation 1: Mary's parents, as described in a) -Generation 2: Mary and her two siblings, one brother and one sister - Generation 3: Mary's children with a normal man: two boys and two girls (you may assume that Mary passes on each X chromosome to exactly half her children) AND her brother's two sons and one daughter with a normal (non-carrier) woman.Explanation / Answer
A.Dd
B.50%
C.50% chances of heterozygous carrier of OTD and 0% chances that daughter will have OTD.
D.the genotype of male will be dY.
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