A 10-month-old Central American child was referred to the laboratory for testing
ID: 145822 • Letter: A
Question
A 10-month-old Central American child was referred to the laboratory for testing after being seen by a pediatrician. The phlebotomist noted that the child was very pale and listless. The following tests were ordered: CBC with platelet, reticulocyte count, total serum bilirubin, total serum iron, and total iron-binding capacity (TIBC), as well as a stool examination for occult blood, ova, and parasites. The results are listed below:
The stool examination was negative for occult blood, ova, and parasites.
How would you classify the child’s anemia morphologically?
Based on the laboratory results provided, what is the most likely cause for anemia in this patient?
What kind of erythrocyte morphology would you expect to observe in the peripheral blood of this patient?
What would the bone marrow look like in this patient if we stained a slide with Wright’s Stain? And with Prussian blue?
What is the appropriate treatment for this disorder?
Parameter Hemoglobin Hematocrit RBC WBC Platelet MCV MCH MCHC Retic count Total serum bilirubin Serum iron Serum ferritin TIBC % Saturation Result 5.6 g/dL 20% 3.5 x 101/L 10.5 x 103/L 200 x 109/L 68.6 fL 16 23% 0.5% 0.9 mg/dl 40 g/dL 5 ng/mL 465 ug/dL 8.6% Reference Range 10.5-13.5 g/dl 33-42% 3.7-5.3x1012/L 6.0-18.0 x 109 150-450 x 109/L 74-91 f 23-31 32-36% 0.5-2.0% 0.3-1.9 mg/dL 50-160 ug/dL 15-400 ng/mL 250-400 ug/dl 20-55%Explanation / Answer
How would you classify the child’s anemia morphologically?
Based on the laboratory results provided, what is the most likely cause for anemia in this patient?
What kind of erythrocyte morphology would you expect to observe in the peripheral blood of this patient?
What would the bone marrow look like in this patient if we stained a slide with Wright’s Stain? And with Prussian blue?
What is the appropriate treatment for this disorder?
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