6. You are studying a biosynthetic pathway. You find that enzyme A converts the

Question

6. You are studying a biosynthetic pathway. You find that enzyme A converts the starting compound into the first intermediate. The first intermediate is converted into the second intermediate by enzyme B. The second intermediate is converted into the product by enzyme C. You make loss-of-function mutations in the genes encoding each of the enzymes. What will the phenotype be if a double-mutant is made between the genes encoding enzyme A and enzyme C? a. Build-up of the starting compound b. Build-up of the first intermediate c. Build-up of the second intermediate d. Production of the product e. None of the above.

Explanation / Answer

And-C

There will be build up of 2nd intermediate becouse enzyme B is converting intermediate 2 but enzyme C is not catalysing the 2nd intermediate conversion

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