15. Imagine that nail color in mouse is controlled by two genes. At locus b, the

Question

15. Imagine that nail color in mouse is controlled by two genes. At locus b, the wild-type allele b+is dominant to the b allele. b+ homozygotes make brown pigment and b homozygotes make blue pigment. Imagine that transport of the pigment into the nail requires a separate locus: The wild-type allele t+ is dominant to the recessive allele t. t+homozygotes transport the blue or brown pigment into the nails, while t homozygotes fail to transport the pigments, resulting in white nails. You mate two animals that are heterozygous at both loci. The ratio of progeny in the next generation will be: a. 3 brown: 1 blue b. 1 brown 2 blue: 1 white c. 9 brown: 3 blue 3 intermediate brown-blue: 1 white d. 9 brown: 3 blue: 4 white e. None of the above

Explanation / Answer

D.9 brown 3 blue 4 white

When dominant allele of 1 gene masks the effect of either allele of other gene then the phenotypic ratio is 9:3:4 in the F2 generation

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