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of the homologous chromosomes. The alleles on the other chromosome are not expre

ID: 145664 • Letter: O

Question

of the homologous chromosomes. The alleles on the other chromosome are not expressed in the same cell. This process is known a a. isotype or class switching DNA recombination allelic exclusion. g, terminal B cell differentiation e. none of these 12. Ear'y in fetal Ife,call begin o ferenihces inthe blood. These cels al ome fom a common precunsor cll.This precursor is called a (an): a. myeloid stem cell b. lymphoid stem cell .hema etc stem cel d. bone marrow stem cell e. erythropoetic stem cel 13. Nuclectide sequences in the DNA allow B-cells to exchange one isotype gene segment for another isotype gene segment are known , recombinaton sigral sequences inducers switich regions ancers. G enhancers d promoters.. 4. Vinuses are able to stimulate cell mediated immunity because: a. peptides from the virus bind to Class I MHC (MHCI) moleaules and are displayed on the surface of inflected cels b. they are extracellular c viral peptides are presented with Abs on B cells d. peptides from the vinus bind to Class II MHC (MHCII) molecules and are displayed on the surtaco of iefected cels e. b and c t a and c g. a, b, and c h. none of the above 15. Which statement is TRUE about ig? a. litte is known about its function and is the loast abundant antibody b. it has 2 subclasses .itusualy occurs as a dirner d. it can be secreted e. it plays a role in triggering allergic responses by binding to eosinophils 16. The Laan gene custer ison a chromosome 32 17. Which of the following is NOT a characteristic of lgG? b. chromosome 22 chromosome 14 chromosome 2 e. chromosome 42 a it is the largest of all the igs b. It crosses the placenta g lt is the predominant immunoglobulin in blood. lymph, and peritoneal fuid d. it contains 2 gamma (g) H chains and 2L chains .its Lchainscan beeiter Kor 18. lsotype switching resembles somatic recombination because both a are catalyzed by the enzyme DNA recombinase b are regulated by T-helper cells g result in the irreversible loss of DNA from the B cel d occur in developing B cellis in the bone marrow e. are reguilated by APCs

Explanation / Answer

11. c Allelic exclusion

12.c Haematopoetic stem cells are the precursor stem cells that differentiate into other cells present in the blood.

13. b - Switch regions are double stranded breaks which are generated in the DNA which allow for immunoglobulin class switching

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