Given the list of the following, place them in correct order. Some of the choice

Question

Given the list of the following, place them in correct order. Some of the choices may be used in multiple pathways, and not all pathways will have 12 items in them. Place the letter in the blanks. Starting from the first process to the last.

A. MAPKK D. Trimeric G-protein G. GTP binding J. GTP hydrolysis M. Diacyl glycerol P. Trans-autophosphorylatiorn R. Inositol tris phosphate (IP3) U. MAPK phosphatase B. Protein Kinase C E. Raf (an MAPKKK) H. Receptor tyrosine kinase K. Ca" release N. MAPK C. cAMP phosphodiesterase F. Transcription factor L. Phospholipase C L. Protein kinase A O. 7-transmembrane receptor Q. IP3-gated channel T. cAMP W. Ras S. Adenylyl cyclase V. GDP release IP3 CAMP RTK IV vi

Explanation / Answer

Receptor protein tyrosine kinase
Trans autophosphorylation
Ras
Raf
MEK MAPKK
ERK MAPK
MAPK phosphatase
Transcription factor

IP3

7-transmembrane receptor
Trimeric G protein
GTP binding
Phospholipase C
IP3 gated channel
IP3
Ca2+ release
Diacyl glycerol
Protein kinase C

cAMP

Adenyl cyclase
cAMP
Protein kinase A
cAMP phosphodiesterase

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