Sickle cell anemia is an autosomal recessive disorder caused by a mutation in th

Question

Sickle cell anemia is an autosomal recessive disorder caused by a mutation in the HBB gene resulting in atypical hemoglobin molecules which adversely affects red blood cells. Two normal parents give birth to a baby with sickle cell anemia. 3. What is the probability that a sperm from the father will contain the HBB mutation? (0.25pt) a. What is the probability that an egg from the mother will contain the HBB mutation? (0.25pt) b. C. What is the probability that their next child will have sickle cell anemia? (0-25pt) What is the probability that their next child will be heterozygous for the HBB mutation? (0.25pt) d.

Explanation / Answer

I believe the correct answer to be:

A) Since father must be heterozygous for the disease to be normal, the probalility should be 0.5

B) Same goes for the mother i.e 0.5

C) Out of four possible combination for the child, only one will result in the condition meaning the probability should be 0.25

D) 2 out of four will be hetrozygous so the probability should be 0.5

Feel free to leave a comment down below for any further query. Good rating would be appretiated if you find my answer helpful. Thank you.

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