a) You decide to study the MN blood group among students. Blood type in the MN b

Question

a) You decide to study the MN blood group among students. Blood type in the MN blood group is determined by a single gene with two alleles: M and N. You manage to get blood samples from 500 students. You determine that 200 of them have the MM blood type, 250 are MN, and 50 are NN. What is the frequency of the M and N alleles in the student population?

b) Using the data from the previous question, what are the expected frequencies of the three blood types among students, assuming Hardy-Weinberg Equilibrium?

Explanation / Answer

A) The frequency of M allele,

= (200 + (250/2))/ 500

= (200 + 125)/500

= 325/500

= 0.65

The frequency of N allele,

= (50 + (250/2)) / 500

= (50 + 125) / 500

= 175/500

= 0.35

B) If the population is in Hardy Weinbergs equilibrium, the expected number of frequencies in each blood types are,

MM = (0.65)(0.65) = 0.4225

MN = 2(0.65)(0.35) = 0.455

NN = (0.35)(0.35) = 0.1225

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