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miRNA-211 is involved in inflammation during acute respiratory distress syndrome

ID: 142358 • Letter: M

Question

miRNA-211 is involved in inflammation during acute respiratory distress syndrome (ARDS). It is possible to genetically engineer mice that exhibit ARDS.

q) which of the following is not true of miRNA.?

A) miRNAs are translated into proteins that impact gene expression of specific gene targets. B) The miRNA transcripts are typically synthesized by Pol 2 and then capped and polyadenylated. C) miRNAs are a class of small RNA molecuels with an average length of 22 nucleotides and the capacity to regulate the expression of many genes. D)all are true

Explanation / Answer

A) miRNA are translated into proteins that impact gene expression of specific gene targets.

miRNA base pairs with the complementary strand of RNA perfectly or near perfectly which degrade the mRNA or it will not allow RNA pol to bind in the promoter region. This will result in inhibition of protein translation of the target RNA and also causes deadenylation.