How would each of the following scenarios affect the influx of Na+ ions into a t

Question

How would each of the following scenarios affect the influx of Na+ ions into a typical cell. Provide the simple answer (“Increase” for increased influx of Na+ or “Decrease” for decreased influx), a brief explanation for the answer, and any information sources you consulted to find the answer.

Example: A bunch of gated sodium channels on the cell open simultaneously.

Increase. Fick’s law states that the rate of diffusion will increase with membrane permeability, and opening ion channels will increase permeability. (sources: Fick’s Law on Wikipedia)

1. A large exocytotic vesicle merges with the cell membrane.

2. A nearby cell pumps an excessive amount of Na+ into the extracellular space.

3. Cholesterol gets added to the membrane.

4. Sudden failure of the Na+/K+ pump.

Explanation / Answer

A large exocytotic vesicle merges with the cell membrane.

increase, To balance the sodium potassium pump.

A nearby cell pumps an excessive amount of Na+ into the extracellular space.

Increase, If the sodium ion concentration high in extracellular space , concentration gradient increase between inside and outside the cell and sodium ion influx increases.

Cholesterol gets added to the membrane.

Decrease. ATPase are involved in transport of ion into cell .Because ATPase activity decrease due to cholestrol influx of sodium ion also decreases

Sudden failure of the Na+/K+ pump

Decrease, Due to breaking of sodium - potassium ion pump movement of ions stopped and Sodium ion concentratio increase in side the cell.

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