The discussion and figure below detail the fact that mesenchymal cells aggregate

Question

The discussion and figure below detail the fact that mesenchymal cells aggregate at the posterior margin of th elimb bud to form the studies show that the SHH signal is relayed to the AER by activation of the BMP antagonist Gremlin rather than acting as a long-range signal (Figure 2). Antagonism of BMP signalling by Gremlin controls AER differentiation and distal-anterior propagation of te SHH signalling centre. Gremlin is not only required for epithelial-mesenchymal signalling interactions during limb development (Figure 2), but also for induction of the definitive metanephric kidney. In Gremlin deficient mouse embryos, outgrowth of the ureteric bud and epithelial-mesenchymal signalling mediated by cRET and GNDF is disrupted. Therefore, the BMP antagonist Gremlin seems to be essential to establishment of epithelial-mesenchymal signalling centres during embryonic pattern formation." http://pages.unibas.ch/anatomie/zeller/seiten/seite1.html select correct choice from list). "Our A Induction BProgression FGF8 FGF8 FGF10 FGF GRE FGF SHH a. zone of polarizing activity o b. apical ectodermal ridge O c. digital rays o d.bone morphometric porteins o e. syndactyly

Explanation / Answer

Answer

A) Zone of polarising Activity

Explanation :It is a cluster of mesenchyme cells located at the posterior border of the limb bud. These contains the signals that instruct the developing limb bud to form along the anterior/posterior axis.

Related Questions

Navigate

• Browse (All)
• Browse T
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.