Lysosomes are membranous orgahelles that contain digestive enzymes. Lysosones ca

Question

Lysosomes are membranous orgahelles that contain digestive enzymes. Lysosones can function inside the cell, where their enzymes digest particles taken in by endocytosis or worn-out cell components Lysosomes can also release their enzymes outside the cell, where the enzymes break down extracellular material. Answer the following questions about conditions related to lysosomal function. l-cell disease is a lysosomal storage disease that results in the buildup of carbohydrates, lipids, and proteins as inclusion bodies within the cell. Which is the probable cause? The cell does not take up food molecules by endocytosis. O Lysosomes accumulate extra lipid-digesting enzymes O The lysosome cannot fuse to the cell membrane to release enzymes extracellularly O The Golgi apparatus cannot target the appropriate enzymes to the lysosome. Rheumatoid arthritis (RA) is an autoimmune disease marked by inflammation and cartilage destruction. Although the causes are not known, it may be linked to lysosomal proteases (protein-digesting enzymes). How may lysosomal proteases be linked to RA? O O Ocollagen. O Cells produce defective lysosomal proteases, which break down proteins inefficiently. Chondroblasts (cells in cartilage) sequester collagen-building enzymes within lysosomes. The lysosomes in cartilage tissue cannot fuse with protein-containing vesicles. Excess lysosomal proteases are produced and released extracellulary, where they degrade

Explanation / Answer

Part-1 Golgi apratus can not target the appropriate enzymes to the lysosomes and that enzymes is phopshptranferases which work as an marker for lysosomes to detect.

Part-2- Excess lysosomal proteases are produced and released extracelluarly, where they degrade collagen

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